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As a general point, digressing with your example--

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I'd have to say that I find Jamison to be a more appealing alternative for a girl than Jamesine or Jamesina because to me they're both just incredibly ugly. I usually like female names that are male names feminized with an -ine ending, but not at all with those. I know there's a lot of debate on the board about the -son ending and if it's only appropriate for one sex, but given how popular and largely accepted -son names are for girls nowadays I'd much rather go with the name that was actually aesthetically pleasing rather than the one that I think sounds more like a playground taunt to an effeminate boy, which is just about how I'd describe Jamesina.

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Not to say there's anything wrong with your opinion or your suggestion, but that very well could be the "why not" behind Jamesine/Jamesina. It's like Madison and Maude; I don't care much for Madison, but I find Maude to be incurably ugly and would greatly prefer going for the -son name instead based on the aesthetic gap between them.