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That particular h in Hebrew has a sort of kh sound - it is pronounced like ch in Scottish loch and is difficult for native English-speakers to say.
Yitzhak is pronounced sort of like yeetz-khahk.
The reason you might have heard the end like -ok is because the Eeastern European (Ashkenazi) pronunciation of Hebrew differs from the Sephardi. The Sephardi pronunciation is -ahk, the Ashkenazi is -ok.
The Sephardi pronunciation is used in Israel, as well as by adherents of the Lubavitcher movement and Reform Judaism.
The Ashkenazi pronunciation is the one still heard in most synagogues.
Outside Israel and Orthodox Jewish circles Isaac would be the name used in everyday life, and the Hebrew pronunciation used when the person called Isaac is involved in the ritual of the synagogue.