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I like it. I don't think it's disrespectful, because it's a place name as well as a tribe name and it's been common for a while.
Plus, if you use it because you admire the culture it isn't disrespectful, is it?
I wouldn't use it but I do like it, with the right middle name (nothing trendy or fillery). I know a few. I like it on a girl only. I don't like other spellings. It would only be trashy if it were Shyann, ShyAnn, Chyanne, etc.
I think the middle name is a lot of it though-- Cheyenne Grace, Cheyenne Kaycee, Cheyenne Kayla, and Cheyenne Elizabeth would be common, but Cheyenne Larkspur or something would be good IMO.