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Caecus (m) and caeca (f) are adjectives meaning 'blind'. Caecilius is that adjective turned into a surname; if borne by a woman, the female form was Caecilia. This was originally a plebeian name, and might well have been used originally to refer to a blind person, or maybe to someone who had a blind spot - a kind of prejudice - about something. The name existed long before Christianity.

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I'm a bit vague about saints, but wasn't St Dunstan the patron of the blind?