for me,
Dean is a good name with positive associations. I could see it becoming more popular, especially with the recent trend in Anglo girls' names towards more old-fashioned choices; something similar might happen, or already be happening, with boys' names.
Gene is not for me, the associations towards DNA, chromosomes and the like are too strong, but I do like
Eugene. the feminine
Eugenie and
Eugenia are also good in my books.