It has occasionally been used as an English given name since the 16th century. It was moderately popular in the 1940s, but had a more notable upswing in the early 2000s. This may have been inspired by the Spanish actress Penélope Cruz (1974-), who gained prominence in English-language movies at that time. It was already rapidly rising when celebrities Kourtney Kardashian and Scott Disick gave it to their baby daughter in 2012.
In England the name became rare after the Middle Ages, but it was revived in the 19th century, more commonly in the spelling Beatrice. Famous bearers include the British author and illustrator Beatrix Potter (1866-1943), the creator of Peter Rabbit, and Beatrix of the Netherlands (1938-), the former queen.
As a given name, it was used on the American sitcom Murphy Brown (1988-1998) for both the mother and son of the main character. By 1998 it was more popular as a name for girls in the United States, perhaps further inspired by a character from the movie Jerry Maguire (1996).