As a given name, it was used on the American sitcom Murphy Brown (1988-1998) for both the mother and son of the main character. By 1998 it was more popular as a name for girls in the United States, perhaps further inspired by a character from the movie Jerry Maguire (1996).
As an English name, Chloe has been in use since the Protestant Reformation. It started getting more popular in the 1980s in the United Kingdom and then the United States. It was the most popular name for girls in England and Wales from 1997 to 2002. This is one of the few English-language names that is often written with a diaeresis, as Chloë.
The name has been very common throughout the English-speaking world since end of the 20th century. In the United States it reached a high point in 2017, when it ranked as the fifth most popular name for boys.
Famous bearers include Peyton Randolph (1721-1775), the first president of the Continental Congress, and American football quarterback Peyton Manning (1976-).
Before 1980, this was an uncommon masculine name in America. During the 1980s and 90s this name steadily increased in popularity for both boys and girls, and from 2003 onwards it has been more common for girls in the United States. Elsewhere in the English-speaking world, such as the United Kingdom and Australia, it has remained largely masculine.
Very rare as an American given name before 1980, it increased in popularity in the 1980s and 90s. It got a boost in 2004 after the debut of the television series Lost, which featured a character by this name.