As a given name, it was used on the American sitcom Murphy Brown (1988-1998) for both the mother and son of the main character. By 1998 it was more popular as a name for girls in the United States, perhaps further inspired by a character from the movie Jerry Maguire (1996).
This name has never been common in the English-speaking world, though it has been well-used elsewhere in Europe. A famous bearer was the Italian Renaissance master Raffaello Sanzio (1483-1520), usually known simply as Raphael in English.
The name was brought to public attention by Samuel A. Taylor's play Sabrina Fair (1953) and the movie adaptation Sabrina that followed it the next year. This is also the name of a comic book character, Sabrina the Teenage Witch, first introduced 1962 and with television adaptations in 1970-1974 and 1996-2003, both causing minor jumps in popularity. Another jump occurred in 1976, when it was used for a main character on the television series Charlie's Angels.
This name was known among the Normans due to the Welsh bishop Saint Samson, who founded monasteries in Brittany and Normandy in the 6th century. In his case, the name may have been a translation of his true Celtic name. As an English name, Samson was common during the Middle Ages, having been introduced by the Normans. It is currently most common in Africa, especially in countries that have an British colonial past.
In the New Testament Simon is the name of several characters, including the man who carried the cross for Jesus. Most importantly however it was borne by the leading apostle Simon, also known as Peter (a name given to him by Jesus).
Because of the apostle, this name has been common in the Christian world. In England it was popular during the Middle Ages, though it became more rare after the Protestant Reformation.