The most notable bearer of the name was Cyrus the Great, the founder of the Achaemenid Persian Empire in the 6th century BC. He is famous in the Old Testament for freeing the captive Jews and allowing them to return to Israel after his conquest of Babylon. As an English name, it first came into use among the Puritans after the Protestant Reformation.
It has never been very common as a given name in the English-speaking world, though it rose in popularity after the middle of the 20th century. In the United States it is frequently an African-American name. In Lithuania it may be given in honour of the Lithuanian-American aviator Steponas Darius (1896-1933), who died attempting to fly nonstop from New York to Lithuania. His surname was an Americanized form of the original Darašius.