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I just thought that as Spears would be pronounced exactly like Speirs an alternative spelling might develop. They often do. I'm thinking, for example, of the Sots name Baird, which sometimes became Beard when removed from its home.
Speirs for Speyer is also a guess. Bentzion Kaganoff's Dictionary of Jewish Surnames is my main source in that area. The Encyclopedia Judaica can be helpful too under individual names. There seem to be several attenuated forms of Speyer as Jewish surnames - Spire, Spiro, even Shapiro. Speirs might be another form, adapted to the English language.