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The De SOUZA surname is associated with the SAQUI surname in Bevis Marks synagogue records of my Sephardic ancestors (ca 1700). Is De SOUZA a toponym? I once heard it meant "happy". Does anyone know if it is a root name or variation of the surname SAQUI? I understand that SAQUI could be a derivation of SAX, or ISAAC, also meaning "one who gives joy"; and there is reference to SAQUI, meaning "fortunate" in Mapuche, an obscure, native South American language. Does anyone know if there is any convincing support linking the surnames SOUZA and SAQUI? Many thanks for help analyzing/supporting/attacking this hypothesis!