Namesakes
Manuel Santana
(m) 1938-2021 
Notable Athletes (tennis)
Carlos Santana
(m) 1947-
Grammy Award Winners 2000 Smooth; Supernatural (record of the year/album of the year)
Notable Musicians
Rock and Roll Hall-of-Famers 1998 Santana
Pedro Santana Lopes
(m) 1956-
Portuguese Presidents and Prime Ministers 2004-2005 (prime minister)
Norberto Téllez
(a.k.a. Santana) (m) 1972-
Olympic Medalists 1992 4x400 m relay (silver)
Rodrigão
(a.k.a. Santana) (m) 1979-
Olympic Medalists 2004; 2008; 2012 volleyball (gold/silver)