Save Type Surname (from location) Usage Spanish, Portuguese Pronounced Pron. /san.ˈta.na/(Spanish) /sɐ̃.ˈtɐ.nɐ/(Portuguese) [key·simplify] Meaning & HistoryExpand Links From any of the numerous places named after Saint Anna. A famous bearer is the Mexican-American musician Carlos Santana (1947-). Related Names RootSanta Ana/Santana (place name) Categories bands, drummers, jockeys, saints