This list is comprised of Spanish Prime Ministers. It includes those from the time of the 1868 Glorious Revolution when Queen Isabella II was overthrown. Since then Spain has been a republic, a constitutional monarchy, a republic again, a dictatorship, and (currently) a constitutional monarchy again. The name of the office in Spanish is Presidente del Gobierno, which is usually translated as Prime Minister since it is the head of government.
| Name | Details | Total |
|---|
| Aznar | 2 prime ministers | 2 |
| Martínez | 2 prime ministers | 2 |
| Sánchez | 2 prime ministers | 2 |
| Aguilar | 1 prime minister | 1 |
| Alcalá | 1 prime minister | 1 |
| Allendesalazar | 1 prime minister | 1 |
| Arias | 1 prime minister | 1 |
| Azaña | 1 prime minister | 1 |
| Azcárraga | 1 prime minister | 1 |
| Barrio | 1 prime minister | 1 |
| Berenguer | 1 prime minister | 1 |
| Blanco | 1 prime minister | 1 |
| Caballero | 1 prime minister | 1 |
| Cabañas | 1 prime minister | 1 |
| Calvo | 1 prime minister | 1 |
| Campos | 1 prime minister | 1 |
| Canalejas | 1 prime minister | 1 |
| Cánovas | 1 prime minister | 1 |
| Carrero | 1 prime minister | 1 |
| Casares | 1 prime minister | 1 |
| Castelar | 1 prime minister | 1 |
| Chapaprieta | 1 prime minister | 1 |
| Correa | 1 prime minister | 1 |
| Dato | 1 prime minister | 1 |
| de Figueroa | 1 prime minister | 1 |
| del Castillo | 1 prime minister | 1 |
| de Zavala | 1 prime minister | 1 |
| Domínguez | 1 prime minister | 1 |
| Fernández | 1 prime minister | 1 |
| Figueras | 1 prime minister | 1 |
| Franco | 1 prime minister | 1 |
| García | 1 prime minister | 1 |
| Giral | 1 prime minister | 1 |
| González | 1 prime minister | 1 |
| Guerra | 1 prime minister | 1 |
| Herrera | 1 prime minister | 1 |
| Jovellar | 1 prime minister | 1 |
| Largo | 1 prime minister | 1 |
| Lerroux | 1 prime minister | 1 |
| López | 1 prime minister | 1 |
| Malcampo | 1 prime minister | 1 |
| Margall | 1 prime minister | 1 |
| Mateo | 1 prime minister | 1 |
| Maura | 1 prime minister | 1 |
| Montero | 1 prime minister | 1 |
| Moret | 1 prime minister | 1 |
| Navarro | 1 prime minister | 1 |
| Negrín | 1 prime minister | 1 |
| Palmero | 1 prime minister | 1 |
| Pi | 1 prime minister | 1 |
| Portela | 1 prime minister | 1 |
| Posada | 1 prime minister | 1 |
| Prieto | 1 prime minister | 1 |
| Prim | 1 prime minister | 1 |
| Primo de Rivera | 1 prime minister | 1 |
| Quiroga | 1 prime minister | 1 |
| Rajoy | 1 prime minister | 1 |
| Ríos | 1 prime minister | 1 |
| Rodríguez | 1 prime minister | 1 |
| Ruiz | 1 prime minister | 1 |
| Sagasta | 1 prime minister | 1 |
| Salmerón | 1 prime minister | 1 |
| Samper | 1 prime minister | 1 |
| Sánchez de Toca | 1 prime minister | 1 |
| Serrano | 1 prime minister | 1 |
| Silvela | 1 prime minister | 1 |
| Soler | 1 prime minister | 1 |
| Sotelo | 1 prime minister | 1 |
| Suárez | 1 prime minister | 1 |
| Valladares | 1 prime minister | 1 |
| Villaverde | 1 prime minister | 1 |
| Zamora | 1 prime minister | 1 |
| Zapatero | 1 prime minister | 1 |
| Zorrilla | 1 prime minister | 1 |