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Yes, Ramachandran is the same as Ramachandra, etc. This particular spelling is doubtless South Indian. The North Indian form would usually be Ramchand, though there are variants. A forename and a surname, as you indicate. Apparently the meaning is "moonlike (God) Rama", and a male given name, so presumably a patronymic.

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Yasir, Yaser, Yasser are the same. The name is said to mean "easy". In the case of the Palestinian leader, Yasir Arafat, it was a nickname.