Save Type Surname (from location) Usage Spanish Pronounced Pron. /de.ˈla.ˈre.ˈɡu.ˈeɾa/ [key·simplify] Meaning & History Means "of the ditch" in Spanish, from Spanish reguera "ditch, irrigation ditch". Ana de la Reguera (1977-) is a Mexican actress known for her role as Sister Encarnación in the 2006 comedy film Nacho Libre.