From Japanese 桜, 櫻 (sakura) meaning "cherry blossom" combined with 井 (i) meaning "well." A notable bearer of this surname is Takahiro Sakurai (櫻井 孝宏), a Japanese voice-actor who is best known for voicing Izuru Kira from Bleach, Kiyomaro Takamine from Zatch Bell, and Ja'far from the Magi series.